Genetic markers in oligodendroglial tumours

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Genetic markers in oligodendroglial tumours

BACKGROUND Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas. CONCLUSIONS Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment....

متن کامل

Tumour markers in pediatric solid tumours

Tumour marker as a term generally refers to developmentally regulated proteins which are expressed in or from neoplastic tissues. Traditionally these proteins were protein or carbohydrate molecules, which were expressed in the fetus during the developmental period, thus these were also known as ‘oncofetal antigens’. In the present era the term ‘tumour marker’ has acquired a broader sense and im...

متن کامل

Molecular imaging of 1p/19q deletion in oligodendroglial tumours with 11C-methionine positron emission tomography

OBJECTIVE Chromosome 1p/19q deletion is an established prognostic and predictive marker in the WHO grade III oligodendroglial tumours (OT). To estimate the genetic status preoperatively, the authors investigated the correlation between the uptake of (11)C-methionine in positron emission tomography (PET) and the 1p/19q status in grades II and III OT. METHODS We retrospectively reviewed 144 pat...

متن کامل

Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI features.

Oligodendroglial neoplasms with the -1p/-19q genotype are more indolent with longer survival and increased therapeutic responsiveness than those with intact 1p/19q, but the biological basis for these clinical differences is unclear. Recent research suggests that oligodendrogliomas with and without the -1p/-19q genotype may be distinguished by their magnetic resonance imaging (MRI) appearance, s...

متن کامل

Molecular imaging of 1p/19q deletion in oligodendroglial tumours with C-methionine positron emission tomography

To cite: Iwadate Y, Shinozaki N, Matsutani T, et al. J Neurol Neurosurg Psychiatry 2016;87: 1016–1021. ABSTRACT Objective Chromosome 1p/19q deletion is an established prognostic and predictive marker in the WHO grade III oligodendroglial tumours (OT). To estimate the genetic status preoperatively, the authors investigated the correlation between the uptake of C-methionine in positron emission t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Radiology and Oncology

سال: 2010

ISSN: 1581-3207,1318-2099

DOI: 10.2478/v10019-010-0007-y